Starting with a review of protein chemistry, emphasizing chemical modification and separation technologies, the course will review current approaches to the study of proteomics, how proteomics interacts with other fields and discuss what is likely to be realized in the next several years.
This course is NOT restricted to graduate students. If you are not a student and are interested in attending, please contact Robert Chalkley.
All lectures will take place from 9:00am - 10:30am in room GH-S202.
|1.||Tue. 1/6||Overview / Protein Chemistry||RAB|
|2.||Thu. 1/8||Protein Purification and Separation/Gels||RJC|
|3.||Tue. 1/13||Peptide Purification and Separation||RAB|
|4.||Thu. 1/15||Introduction to Mass Spectrometry||RJC|
|5.||Tue. 1/20||Protein ID 1 – Non-MS||RAB|
|6.||Thu. 1/22||Protein ID 2 – MS||RJC|
|7.||Tue. 1/27||Protein Annotation / Computational Biology||PCB|
|8.||Thu. 1/29||Biophysical Methods (Fluorescence / Hydrodynamics)||RAB|
|9.||Tue. 2/3||Quantification using MS||KFM|
|10.||Thu. 2/5||Protein – Protein Interactions: TAP; Crosslinking||RJC|
|11.||Tue. 2/10||Protein – Protein Interactions: Intact Complex Analysis||KFM|
|12.||Thu. 2/12||Protein Machines / Sociology||AS|
|13.||Tue. 2/17||PTMs – Enrichment||KFM|
|14.||Thu. 2/19||PTMs – MS Identification and Assessing Reliability||RJC|
|15.||Tue. 2/24||PTMs – Complex / Crosstalk||KFM|
|18.||Thu. 3/5||Network Analysis and Clustering||RJC|
|19.||Tue. 3/10||Translational / Biomarkers||RAB|
|20.||Thu. 3/12||Interaction with other OMICS||RJC, KFM, RAB|
In addition to attending the lectures, students taking this course for credit will be required to select and present a review of a published paper (from a pool of papers selected by the instructors). These will be presented during the last half hour of several of the later lectures in the series. Students will also be expected to write a paper on a topic of current interest to the field (from a list provided, or select their own topic after instructor approval).
For more details contact course organizer: Robert Chalkley.