Shenheng Guan

Shenheng Guan


Adjunct Professor



BS: 1982, Physical Chemistry, Fudan University, Shanghai, China
PhD: 1989, Analytical Chemistry, University of the Pacific, Stockton, CA

Work History

2011-present: Adjunct Professor, Department of Pharmaceutical Chemistry, UCSF, CA
2004-2011: Associate Adjunct Professor, Department of Pharmaceutical Chemistry, UCSF, CA
1996-2003: Distinguished Scientist, Symyx Technologies, Santa Clara, CA
1993-1996: Associate Director, ICR program, National High Magnetic Field Laboratory, Tallahassee, FL
1991-1993: Postdoctoral and Research Associate, Department of Chemistry, Ohio State University, Columbus, OH
1990-1991: Postdoctoral Researcher, Department of Pharmaceutical Chemistry, UCSF, CA
1989-1990: Postdoctoral Researcher, Department of Chemistry, University of California, Irvine, CA

Research Interests

Select Publications

Shenheng Guan, and A. L. Burlingame, "Data Processing Algorithms for Analysis of High Resolution MSMS Spectra of Peptides with Complex Patterns of Posttranslational Modifications", Molecular and Cellular Proteomics, published online: Nov. 25, 2009.

Shenheng Guan, and A. L. Burlingame, "High Mass Selectivity for Top-down Proteomics by Application of SWIFT Technology", Journal of American Society for Mass Spectrometry, 2009, 21, 455-459.

Tae-Wuk Kim, Shenheng Guan, Yu Sun, Zhiping Deng, Wenqiang Tang, Jian-Xiu Shang, Ying Sun, Alma L. Burlingame & Zhi-Yong Wang, "Brassinosteroid signal transduction from cell-surface receptor kinases to nuclear transcription factors", Nature Cell Biology, 2009, 11, 1254-1260.

Ronald A. McCord, Eriko Michishita, Tao Hong, Elisabeth Berber, Lisa D. Boxer, Rika Kusumoto, Shenheng Guan, Xiaobing Shi, Or Gozani, Alma L. Burlingame, Vilhelm A. Bohr, and Katrin F. Chua, "SIRT6 stabilizes DNA-dependent Protein Kinase at chromatin for DNA double-strand break repair", Aging, 2009,1, 109-121.

Paula Casatia, Mabel Campia, Feixia Chu, Nagi Suzuki, David Maltby, Shenheng Guan, Alma L. Burlingame and Virginia Walbot, "Histone Acetylation and Chromatin Remodeling Are Required for UV-B-Dependent Transcriptional Activation of Regulated Genes in Maize", The Plant Cell 2008, 20, 827-842.

National Institute of General Medical Sciences Adelson Medical Research Foundation