Professional Research Chemist/Adjunct Professor of Pharmaceutical Chemistry
| Ph.D. | Organic Chemistry | 1981 | Eötvös Lóránd University, Budapest, Hungary |
| M.Sc. | Organic Chemistry | 1976 | Eötvös Lóránd University, Budapest, Hungary |
| 2006-Present: | Adjunct Professor, Department of Pharmaceutical Chemistry, UCSF, CA |
| 2006-Present: | Professional Research Biochemist, Department of Pharnaceutical Chemistry, UCSF, CA |
| 2004-2006: | Associate Adjunct Professor, Department of Pharmaceutical Chemistry, UCSF, CA |
| 2000-Present: | Head of the Proteomics Research Group/Mass Spectrometry Facility, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary. |
| 1996-2006: | Associate Research Biochemist, Department of Pharnaceutical Chemistry, UCSF, CA |
| 1993-1996: | Assistant Research Biochemist, Department of Pharmaceutical Chemistry, UCSF, CA |
| 1991-1993: | Assistant Research Chemist, Department of Pharmaceutical Chemistry, UCSF, CA |
| 1988-1991: | Postdoctoral Fellow, Department of Pharmaceutical Chemistry, UCSF, CA |
| 1980-1987: | Scientist, Gedeon Richter Ltd., Budapest, Hungary |
| 1980-1987: | Scientist, Central Research Institute of Chemistry/Chinoin, Budapest, Hungary |
mass spectrometry; collision-induced dissociation; electron-transfer dissociation; protein analysis, proteomics, de novo sequencing; post-translational modifications; glycosylation; phosphorylation, sulfation; side-reactions.
2004 to present - Molecular & Cellular Proteomics - Editorial Board
Medzihradszky KF and Chalkley RJ. Lessons in de novo peptide sequencing by tandem mass spectrometry. Mass Spectrometry Reviews, Article first published online: 29 OCT 2013, DOI: 10.1002/mas.21406
Trinidad JC, Schoepfer R, Burlingame AL, Medzihradszky KF. N- and o-glycosylation in the murine synaptosome. Mol Cell Proteomics 12(12), 3474-88 (2013). [Pubmed]
McCusker KP, Medzihradszky KF, Shiver AL, Nichols RJ, Yan F, Maltby DA, Gross CA, Fujimori DG. Covalent intermediate in the catalytic mechanism of the radical S-adenosyl-L-methionine methyl synthase RlmN trapped by mutagenesis. J Am Chem Soc. 134(43),18074-81 (2012). [Pubmed]
Darula Z, Sherman J, Medzihradszky KF. How to dig deeper? Improved enrichment methods for mucin core-1 type glycopeptides. Mol Cell Proteomics. 11(7), O111.016774 (2012). [Pubmed]
Bohlen CJ, Chesler AT, Sharif-Naeini R, Medzihradszky KF, Zhou S, King D, Sánchez EE, Burlingame AL, Basbaum AI, Julius D. A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain. Nature. 479(7373), 410-4 (2011). [Pubmed]
Chalkley RJ, Baker PR, Medzihradszky KF, Lynn AJ, Burlingame AL. In-depth analysis of tandem mass spectrometry data from disparate instrument types, Mol Cell Proteomics. 7(12), 2386-98 (2008). [Pubmed]
Tomizawa M, Talley TT, Maltby D, Durkin KA, Medzihradszky KF, Burlingame AL, Yalor P, Casida JE. Mapping the elusive neonicotinoid binding site, Proc Nat Acad Sci USA 104(21), 9075-9080 (2007). [Pubmed]
