Program
This Symposium has Concluded
August: 21 | 22 | 23 | 24 | 25
Sunday, August 21
Symposium Registration
Nikko Ballroom Vestibule, Hotel Nikko, 222 Mason Street, San Francisco
| 3:00 - 5:30pm | Registration | |
Monterey & Carmel Rooms
| 4:00pm | Symposium Poster Set-up | |
Golden Gate Room, 25th floor
| 6:00pm | Opening Reception | |
Monday, August 22
Nikko Ballroom Vestibule
| 7:30am | Registration | |
Symposium
Nikko Ballroom
| 8:15am | Introduction A.L. Burlingame and John Stults |
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Chair: John Stults, Genentech, Inc., South San Francisco, California, USA
| 8:30am | 1.1 | Plenary Lecture The Architecture and transport mechanism of the nuclear pore complex Michael P. Rout, The Rockefeller University, New York, New York, USA |
Chair: John Stults, Genentech, Inc., South San Francisco, California, USA
| 9:30 | 1.2 | Development of mass spectrometer systems for resonance electron capture ionization and radio-frequency-free collision-induced and electron-capture dissociation
Douglas F. Barofsky, Oregon State University, Corvallis, Oregon, USA |
| 10:10 | Coffee break | |
| 10:30 | 1.3 | Structural determination of biological macromolecules using ETD implemented on a hybrid ion mobility quadrupole time-of-flight mass spectrometer Keith Compson, Waters Corporation, Manchester, UK |
| 11:10 | 1.4 | How high mass accuracy measurements will transform targeted proteomics Joshua Coon, University of Wisconsin, Madison, Wisconsin, USA |
| 11:50 | 1.5 | Discovery and preliminary characterization of new lysine modifications Yingming Zhao, University of Chicago, Illinois, USA |
| 12:30pm | Lunch | |
Chair: A.L. Burlingame, University of California, San Francisco, California, USA
| 2:00 | 1.6 | Phosphatase interactomes — towards a quantitative view of interaction dynamics Anne-Claude Gingras, Samuel Lunenfeld Research Institute at Mount Sinai Hospital, Toronto, Ontario, Canada |
| 2:40 | The MCP Lectureship Barbara Gordon, ASBMB, Bethesda, Maryland, USA |
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| 2:45 | 1.7 | MCP Plenary Lecture Technology and applications of deep proteome sequencing Matthias Mann, Max Planck Institute of Biochemistry, Martinsried, Germany |
Symposium Poster Session A
Monterey & Carmel Rooms
Co-Chairs: Shenheng Guan and David Maltby, University of California, San Francisco, California, USA
| 4:00 | Poster Session A | |
Tuesday, August 23
Symposium
Nikko Ballroom
Chair: Barbara Panning, University of California, San Francisco, California, USA
| 8:30am | 2.1 | Plenary Lecture The ATAC acetyltransferase complex coordinates the association and activity of MAP kinases on JNK target genes Jerry Workman, Stowers Institute for Medical Research, Kansas City, Missouri, USA |
Chair: Joshua Coon, University of Wisconsin, Madison, Wisconsin, USA
| 9:30 | 2.2 | Long distance combinatorial histone posttranslational modification changes in DNA damage response and repair processes Nicolas L. Young, Princeton University, New Jersey, USA |
| 10:10 | Coffee break | |
| 10:30 | 2.3 | The good, the bad, and the ugly of using ChIP antibodies as tools to study histone modifications: A proteomics approach Jacob Jaffe, Broad Institute, Cambridge, Massachusetts, USA |
| 11:10 | 2.4 | Analysis of the relationship between O-GlcNAc and polycomb-mediated transcriptional regulation in embryonic stem cell maintenance Samuel Myers, University of California, San Francisco, California, USA |
| 11:50 | 2.5 | Large scale analysis of synaptic phosphorylation and O-GlcNAcylation reveals complex interplay between these post-translational modifications. Jonathan Trinidad, University of California, San Francisco, California, USA |
| 12:30pm | Lunch | |
Chair: Lan Huang, University of California, Irvine, California, USA
| 2:00 | 2.6 | Global kinetics analysis of the apoptotic caspases via targeted proteomics Nicholas Agard, Codexis, Inc., Redwood City, California, USA |
| 2:40 | 2.7 | Defining the druggable cysteinome Jack Taunton, University of California, San Francisco, California, USA |
| 3:20 | 2.8 | Modification site assignment scoring: Phosphorylation and beyond Robert Chalkley, University of California, San Francisco, California, USA |
Co-Chairs: Katalin Medzihradszky and Victoria Pando, University of California, San Francisco, California, USA
| 4:00 | Poster Session B | |
Wednesday, August 24
Symposium
Nikko Ballroom
Chair: Jonathan Trinidad, University of California, San Francisco, California, USA
| 8:30am | 3.1 | Receptor tyrosine kinases: Devolving signaling components with phosphoproteomics Ralph A. Bradshaw, University of California, San Francisco, California, USA |
| 9:10 | 3.2 | Chemical genetic approach for kinase substrate identification reveals novel substrates of NDR1 and uncovers their role in controlling dendrite arborization and synapse maturation Nicholas Hertz, University of California, San Francisco, California, USA |
| 9:50 | 3.3 | Phosphoproteomics reveals multiple Aurora substrates involved in chromatin dynamics Boris Maček, Proteome Center Tuebingen, Tuebingen, Germany |
| 10:30 | Coffee break | |
Chair: A.L. Burlingame, University of California, San Francisco, California, USA
| 10:50 | 3.4 | Plenary Lecture Discovery and targeted proteomic approaches for the study of aging and age-related diseases Bradford W. Gibson, Buck Institute for Research on Aging, Novato, California, USA |
| 11:50 | Lunch | |
Chair: Jeffrey Gorman, Queensland Institute of Medical Research, Herston, Australia
| 1:20pm | 3.5 | Defining protein interaction networks of protein complexes to understand their function and regulation Lan Huang, University of California, Irvine, California, USA |
| 2:00 | 3.6 | Sampling the topography of protein complexes by chemical crosslinking in conjunction with high resolution ETD-MS/MS analysis Michael Trnka, University of California, San Francisco, California, USA |
Symposium Poster Session C
Monterey & Carmel Rooms
Co-Chairs: Robert Chalkley and Juan Oses, University of California, San Francisco, California, USA
| 2:40 | Poster Session C | |
Conference Dinner
Julia Morgan Ballroom
| 6:00pm | Conference Dinner Reception Julia Morgan Ballroom |
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| 7:00 | Conference Dinner Julia Morgan Ballroom |
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Thursday, August 25
Symposium
Nikko Ballroom
Chair: Juan Oses, University of California, San Francisco, California, USA
| 8:30am | 4.1 | Development of a physicochemically diverse peptide library for multiplexed profiling of protease specificity Giselle Knudsen, University of California, San Francisco, California, USA |
| 9:10 | 4.2 | Targeted identification of SUMOylation sites in human cells using affinity enrichment and paralog-specific reporter ions on a LTQ-Orbitrap Velos Pierre Thibault, University of Montreal, Quebec, Canada |
| 9:50 | 4.3 | Mass spectrometry approaches for profiling ubiquitination Donald S. Kirkpatrick, Genentech, Inc., S. San Francisco, California, USA |
| 10:30 | Coffee break | |
| 11:00 | 4.4 | Methods for characterizing protein ubiquitination in whole cell lysates Namrata Udeshi, Broad Institute, Cambridge, Massachusetts, USA |
| 11:40 | Lunch | |
Chair: Giselle Knudsen, University of California, San Francisco, California, USA
| 1:40pm | 4.5 | Interactions of paramyxoviruses with host cell proteins Jeffrey Gorman, Queensland Institute of Medical Research, Herston, Australia |
| 2:20 | 4.6 | Discovery of antiviral roles of Mammalian Sirtuins: A systems biology view Ileana Cristea, Princeton University, New Jersey, USA |
| 3:00 | 4.7 | Assessing the mechanism of action of tyrosine kinase inhibitors using quantitative phosphoproteomic mass spectrometry Jennifer Gajan, University of California, San Francisco, California, USA |
Chair: John Stults, Genentech, Inc., South San Francisco, California, USA
| 3:40 | 4.8 | Plenary Lecture Novel predictors of cardiometabolic diseases Robert E. Gerszten, Massachusetts General Hospital, Boston, Massachusetts, USA |
| 4:40 | Closing remarks | |
| 5:00pm | Adjourn | |
