Mark A. Burlingame


Instrumentation Laboratory Manager



Ph.D. Organic Chemistry 1996 U.C. Berkeley, California
B.S. Chemistry 1991 SFSU, California

Work History

2014-Present: Instrumentation Lab Manager, Mass Spectrometry Facility, UCSF CA
2013-2014: Engineer, Neurology, UCSF CA
2006-20013: Research Chemist, Small Molecule Discovery Center, UCSF, CA
1998—2006: Senior Scientist, Chemistry, Kosan Biosciences, CA
1996—1998: Post-Doctoral Fellow, Chemistry, Novartis Pharma, Basel, Switzerland

Research Interests

I manage the mass spectrometry facility service laboratory. I have 15 years of laboratory experience, primarily as the main instrumentation person, in addition to my other responsibilities pursuing medicinal chemistry and solving chemical problems. My electronics degree has allowed me to provide a comprehensive understanding of, and ability to troubleshoot, most laboratory equipment including mass spectrometers. My responsibilities in the lab include instrument maintenance, instrument tuning and setup, training of new personnel and the analyses of that component of our samples that are considered of a service nature and not a collaborative project.

Select Publications

Shaw SJ, Sundermann KF, Burlingame M, Zhang D, Petryka J, Myles DC. A series of 23,24-dihydrodiscodermolide analogues with simplified lactone regions. Bioorg Med Chem Lett. 2006 Apr 1; 16(7):1961-4. Epub 2006 Jan 18. PMID: 16413186. [Pubmed]

Ashley GW, Burlingame M, Desai R, Fu H, Leaf T, Licari PJ, Tran C, Abbanat D, Bush K, Macielag M. Preparation of erythromycin analogs having functional groups at C-15. J Antibiot (Tokyo). 2006 Jul; 59(7):392-401. PubMed PMID: 17025015. [Pubmed]

Ashley Gary, Burlingame M, Chan-Kai, Isaac (2006) US Patent 7,022,825 Polyketides and Antibiotics.

Myles David, Burlingame M, Shaw Simon, Sundermann Kurt, Freeze Brian, Martin Ignacio, Hirose Tomoyasu, Smith Amos III (2008), US Patent 7,595,300 7-quinolyl ketolide antibacterial agents Synthetic techniques and intermediates for polyhydroxy dienyl lactones and mimics thereof

Shaw Simon, Ashley Gary, Burlingame M, (2009) US Patent 7,595,300 7-quinolyl ketolide antibacterial agents.

Sadowsky JD, Burlingame M, Wolan DW, McClendon CL, Jacobson MP, Wells JA. Turning a protein kinase on or off from a single allosteric site via disulfide trapping. Proc Natl Acad Sci U S A. 2011 Apr 12; 108(15):6056-61. doi: 10.1073/pnas.1102376108. Epub 2011 Mar 23. PubMed PMID: 21430264; PubMed Central PMCID: PMC3076885. [Pubmed]

Bennallack PR, Bewley KD, Burlingame M, Robison RA, Miller SM, Griffitts JS. J Bacteriol. 2016 Aug 25; 198(18):2431-8. doi: 10.1128/JB.00396-16. Print 2016 Sep 15. PMID:27381911 [Pubmed]

Bewley KD, Bennallack PR, Burlingame M, Robison RA, Griffitts JS, Miller SM. Proc Natl Acad Sci U S A. 2016 Nov 1; 113(44):12450-12455. Epub 2016 Oct 17. PMID:27791142 [Pubmed]

Nakamura RL, Burlingame M, Yang S, Crosby DC, Talbot DJ, Chui K, Frankel AD, Renslo AR. Antimicrob Agents Chemother. 2017 Jun 27; 61(7). pii: e02366-16. Print 2017 Jul. PMID: 28416550 [Pubmed]

National Institute of General Medical Sciences Adelson Medical Research Foundation