Anatoly Urisman

Anatoly Urisman


Assistant Professor



M.D. Medicine 2008 University of California, San Francisco
Ph.D. Biomedical Sciences 2006 University of California, San Francisco

Work History

2016-Present: Assistant Professor, Department of Pathology, University of California, San Francisco
2014-2016: Clinical Instructor, Department of Pathology, University of California, San Francisco
2011-2014: Clinical Research Fellow, Department of Pathology, University of California, San Francisco
2010-2011: Pulmonary Pathology Fellow, Department of Pathology, University of California, San Francisco
2008-2010: Residency, Anatomic Pathology, University of California, San Francisco

Research Interests

My research is focused on understanding cell signaling events involved in the progression of lung cancer. Specifically, we are using targeted proteomic techniques based on SRM mass spectrometry to study phosphorylation dynamics in a large set of proteins involved in EGFR/RAS/ERK signaling. The studies are aimed at identifying key regulatory phosphorylation sites relevant to tumor development, progression, response to targeted therapies, and development of resistance. As part of this effort, we are working on novel approaches for quantifying site-specific phosphorylation of low-abundance proteins, such as transcription factors and other nuclear targets of the intracellular signal transduction pathways.

Select Publications

Greenland JR, Jones KD, Hays SR, Golden JA, Urisman A, Jewell NP, Caughey GH,Trivedi NN. Association of Large-Airway Lymphocytic Bronchitis with Bronchiolitis Obliterans Syndrome. Am J Respir Crit Care Med. (2012 Dec 13) [Epub ahead of print] [Pubmed]

Lee D, Das Gupta J, Gaughan C, Steffen I, Tang N, Luk KC, Qiu X, Urisman A, Fischer N, Molinaro R, Broz M, Schochetman G, Klein EA, Ganem D, Derisi JL, Simmons G, Hackett J Jr, Silverman RH, Chiu CY. In-depth investigation of archival and prospectively collected samples reveals no evidence for XMRV infection in prostate cancer. PLoS One. 7(9) e44954.(2012) [Pubmed]

Nijagal A, Jelin E, Feldstein VA, Courtier J, Urisman A, Jones KD, Lee H, Hirose S, MacKenzie TC. The diagnosis and management of intradiaphragmatic extralobar pulmonary sequestrations: a report of 4 cases. J Pediatr Surg. 47(8) 1501–5.(2012) [Pubmed]

Urisman A, Leard LE, Nathan M, Elicker BM, Hoopes C, Kukreja J, Jones KD. Rapidly progressive pulmonary venoocclusive disease in young women taking oral contraceptives. J Heart Lung Transplant. 31(9) 1031–6.(2012) [Pubmed]

Jones KD, Urisman A. Histopathologic approach to the surgical lung biopsy in interstitial lung disease. Clin Chest Med. 33(1) 27–40.(2012) [Pubmed]

Chiu CY, Urisman A, Greenhow TL, Rouskin S, Yagi S, Schnurr D, Wright C, Drew WL, Wang D, Weintrub PS, Derisi JL, Ganem D. Utility of DNA microarrays for detection of viruses in acute respiratory tract infections in children. J Pediatr. 153(1) 76–83.(2008) [Pubmed]

Chiu CY, Rouskin S, Koshy A, Urisman A, Fischer K, Yagi S, Schnurr D, Eckburg PB, Tompkins LS, Blackburn BG, Merker JD, Patterson BK, Ganem D, DeRisi JL.Microarray detection of human parainfluenzavirus 4 infection associated with respiratory failure in an immunocompetent adult. Clin Infect Dis. 43(8) e71–6. (2006) [Pubmed]

Urisman A, Molinaro RJ, Fischer N, Plummer SJ, Casey G, Klein EA, Malathi K, Magi-Galluzzi C, Tubbs RR, Ganem D, Silverman RH, DeRisi JL. Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant. PLoS Pathog. 2(3) e25.(2006) [Retraction in: PLoS Pathog. (2012) 8(9)] [Pubmed]

Urisman A, Fischer KF, Chiu CY, Kistler AL, Beck S, Wang D, DeRisi JL. E-Predict: a computational strategy for species identification based on observed DNA microarray hybridization patterns. Genome Biol. 6(9) R78. (2005) [Pubmed]

Wang D, Urisman A, Liu YT, Springer M, Ksiazek TG, Erdman DD, Mardis ER, Hickenbotham M, Magrini V, Eldred J, Latreille JP, Wilson RK, Ganem D, DeRisi JL. Viral discovery and sequence recovery using DNA microarrays. PLoS Biol. 1(2) E2.(2003) [Pubmed]

National Institute of General Medical Sciences Adelson Medical Research Foundation