Samuel Myers
Position
Graduate Student
Education
| Ph.D. | Chemistry & Chemical Biology | 2008-Present | University of California, San Francisco |
| B.Sc. | Biochemistry | 2007 | California Polytechnic State University, San Luis Obispo, CA |
Work History
| 2008-Present: | Graduate Student, Mass Spectrometry Facility, UCSF, CA |
| 2007-2008: | Staff Research Associate, Department of Chemical Engineering, University of California, Berkeley |
Research Interests
My interests lie in the post-translational modifications embryonic stem cells use to maintain pluripotency or regulate differentiation. Specifically, I am interested in O-GlcNAcylation, proteolysis and ubiquitination on a global scale. I am also interested in the optimization of electron transfer dissociation strategies to examine labile peptide modifications.
Select Publications
Myers, S., Panning, B., Burlingame,A., Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells, Proc Natl Acad Sci U S A. 108(23), 9490-5 (2011). [Pubmed]
Tang, Y.J., Shui, W., Myers, S., Feng, X., Bertozzi, C., Keasling, J.D., Central metabolism in Mycobacterium smegmatis during the transition from O2-rich to O2-poor conditions as studied by isotopomer-assisted metabolite analysis, Biotechnol Lett. 31(8), 1233-40 (2009). [Pubmed]
Tang, Y.J., Sapra, R., Joyner, D., Hazen, T.C., Myers, S., Reichmuth, D., Blanch, H., Keasling, J.D., Analysis of metabolic pathways and fluxes in a newly discovered thermophilic and ethanol-tolerant Geobacillus strain, Biotechnol Bioeng. 102(5), 1377-86 (2009). [Pubmed]
Tang, Y.J., Martin, H.G., Myers, S., Rodriguez, S., Baidoo. E.E., Keasling, J.D., Advances in analysis of microbial metabolic fluxes via (13)C isotopic labeling, Mass Spectrom Rev. 28(2), 362-75 (2009). [Pubmed]
Steen, E.J., Chan, R., Prasad, N., Myers, S., Petzold, C.J., Redding, A., Ouellet, M., Keasling, J.D., Metabolic engineering of Saccharomyces cerevisiae for the production of n-butanol, Microb Cell Fact. 7, 36 (2008). [Pubmed]