Education
| Ph.D. | Cell Biology | 2009 | Duke University, Durham, NC |
| B.S. | Molecular Biology | 2003 | University of Pittsburgh, Pittsburgh, PA |
Work History
| 2015-Present: | Assistant Researcher, Department of Pharmaceutical Chemistry, University of California, San Francisco |
| 2013-2015: | Postdoctoral Employee, Department of Pharmaceutical Chemistry, University of California, San Francisco |
| 2010-2012: | Postdoctoral Fellow, Molecular Carcinogenesis, National Institute of Environmental Health Sciences (NIEHS), Durham, NC |
Research Interests
I am interested in development and optimization of strategies for large scale isolation of posttranslational modified proteins, including phosphorylation, O-GlcNAcylation, and ubiquitinylation, from different cell and tissue types. While at Duke University, I was trained in cell and molecular biology while I studied the endoplasmic reticulum chaperone GRP94 and its role in Drosophila development and gut function.
Select Publications
Kim S, Maynard JC, Strickland A, Burlingame AL, Milbrandt J. Schwann cell O-GlcNAcylation promotes peripheral nerve remyelination via attenuation of the AP-1 transcription factor JUN. Proc Natl Acad Sci U S A. 2018 07 31; 115(31):8019-8024 PMID: 30012597. PMCID: PMC6077742 [Pubmed]
Kim S, Maynard JC, Sasaki Y, Strickland A, Sherman DL, Brophy PJ, Burlingame AL, Milbrandt J. Schwann Cell O-GlcNAc Glycosylation Is Required for Myelin Maintenance and Axon Integrity. J Neurosci. 2016 Sep 14; 36(37):9633-46. PMID: 27629714. PMCID: PMC5039245 [Pubmed]
Maynard JC, Burlingame AL, Medzihradszky KF. Cysteine S-linked N-acetylglucosamine (S-GlcNAcylation), A New Post-translational Modification in Mammals. Mol Cell Proteomics. 2016 Nov; 15(11):3405-3411. PMID: 27558639. PMCID: PMC5098038 [Pubmed]
Maynard JC, Rankin HB, Pham T, Zheng T, Newgard CB, Spana EP, Nicchitta CV. Gp93, the Drosophila GRP94 ortholog, is required for gut epithelial homeostasis and nutrient assimilation-coupled growth control. Dev Biol. 339(2) 295–306. (2010) [Pubmed]
Chu F, Maynard JC, Chiosis G, Nicchitta CV, Burlingame AL. Identification of novel quaternary domain interactions in the Hsp90 chaperone, GRP94. Protein Sci. 15(6)1260–9. [Pubmed]
